Title :
Simulated Mossy Fiber Associated Feedforward Circuit Functioning as a Highpass Filter
Author :
Zalay, Osbert C. ; Bardakjian, Berj L.
Author_Institution :
Inst. for Biomater. & Biomed. Eng., Toronto Univ., Ont.
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
Learning and memory rely on the strict regulation of communication between neurons in the hippocampus. The mossy fiber (MF) pathway connects the dentate gyrus to the auto-associative CA3 network, and the information it carries is controlled by a feedforward circuit combining disynaptic inhibition with monosynaptic excitation. Analysis of the MF associated circuit using a mapped clock oscillator (MCO) model reveals the circuit to be a highpass filter
Keywords :
brain; neurophysiology; physiological models; auto-associative CA3 network; dentate gyrus; disynaptic inhibition; feedforward circuit; highpass filter; hippocampus; learning; mapped clock oscillator model; monosynaptic excitation; neurons; simulated mossy fiber; Circuit simulation; Clocks; Coupling circuits; Encoding; Filters; Hippocampus; Neurons; Nonlinear dynamical systems; Oscillators; Portals;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260702
