• DocumentCode
    472150
  • Title

    Prototyping Virtual Cancer Therapist (VCT): A Software Engineering Approach

  • Author

    Liu, S. ; Gaudiot, J.L. ; Cristini, V.

  • Author_Institution
    Henry Samueli Sch. of Eng., California Univ., Irvine, CA
  • fYear
    2006
  • fDate
    Aug. 30 2006-Sept. 3 2006
  • Firstpage
    5424
  • Lastpage
    5427
  • Abstract
    This paper proposes the virtual cancer therapist (VCT), a scalable and robust cancer expert system that makes cancer diagnosis, recommends therapy plans, and simulates therapy plans in silico. This system consists of an evaluation core that makes prognosis and chemotherapy simulations, a biomedical database that supports therapy planning, and an optimizer module that makes cancer diagnosis and produces queries for the optimal therapy plans. With the support of its patient record database and simulation core, VCT can also be used to establish an in silico drug discovery standard that dramatically reduces the drug discovery timeline and cost. The prototype of VCT presented in this paper has not only demonstrated the capability of VCT but also identified problems that need to be addressed in the next cycle of development
  • Keywords
    cancer; database management systems; drugs; medical diagnostic computing; medical expert systems; medical information systems; patient treatment; software prototyping; tumours; virtual prototyping; biomedical database; cancer diagnosis; chemotherapy simulations; in silico drug discovery standard; optimizer module; patient record database; prognosis; robust cancer expert system; software prototyping; therapy planning; virtual cancer therapist; Cancer; Databases; Diagnostic expert systems; Drugs; Medical expert systems; Medical treatment; Robustness; Software engineering; Software prototyping; Virtual prototyping;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
  • Conference_Location
    New York, NY
  • ISSN
    1557-170X
  • Print_ISBN
    1-4244-0032-5
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2006.259230
  • Filename
    4463031