A novel classifier for influenza a viruses based on SVM and logistic regression

In search of good classifier of hosts of influenza A viruses is an important issue to prevent pandemic flu. The hemagglutinin protein in the virus genome is the major molecule that determining the range of hosts. In this paper, a novel classification algorithm of hemagglutinin proteins integrating SVM and logistic regression based on 4 kinds of Hurst exponents for each protein sequence is proposed. This method not used before is the first one integrating the physicochemical properties, fractal property, SVM and logistic regression classifier. For evaluating the performance of this new algorithm, a real data experiment by using 5-fold Cross-Validation accuracy is conducted. Experimental result shows that this new classification algorithm is useful and batter than SVM and logistic regression, respectively.