Automated Control of Arterial Pressure and Cardiac Output with Nitroprusside and Dobutamine in Anesthetized Dogs

The Control Advance Moving Average Controller, a modification of the Minimum Variance Self-Tuning Controller, Was used to simultaneously control Mean Arterial Pressure and Cardiac Output in anesthetized dogs. By varying the infusion of sodium nitroprusside and dobutamine the controller successfully lowered the mean arterial pressure and raised the cardiac output to preset setpoints.