Intelligent Control for Cell Culture Processes

An Integrated Intelligent System is being developed for cell culture process control, which consists of several symbolic reasoning systems and numerical computation packages. These software programs are written in different languages and can be used independently. They are under the control of a supervisory expert system, namely, the Meta-System. The key issue to construct the Integrated Intelligent System is to organize the Meta-System. The Meta-System manages the selection, operation and communication of these programs. This new system can diagnose measurement and actuator failures, abnormal process conditions, and select and activate the most suitable control technique for the particular process conditions. It can also serve as a universal configuration to develop high-performance intelligent systems for many complicated engineering applications.