Title :
A biokinematic computational procedure for protein function simulation
Author :
Diez, Mikel ; Petuya, Víctor ; Urizar, Mónica ; Hernández, Alfonso
Author_Institution :
Dept. of Mech. Eng., Univ. of the Basque Country, Bilbao, Spain
Abstract :
Proteins play an essential role in biochemical processes. Recently, a new viewpoint has arisen within protein researches, based on the parallelisms between proteins and mechanisms. In this paper the authors present new methodologies to obtain protein motion paths based in computational kinematic considerations. A Potential Energy field formula for future evaluations is presented. Also, a refinement algorithm to reduce errors in experimental data is introduced. Finally, simulation results for an specific protein are presented.
Keywords :
biochemistry; kinematics; proteins; bio-reconfiguration engineering; biochemical processes; biokinematic computational procedure; computational kinematic considerations; protein function simulation; protein motion; Bioinformatics; Computational modeling; Crystallography; Genomics; Humans; Kinematics; Magnetic analysis; Nuclear magnetic resonance; Potential energy; Protein engineering; Bio-reconfiguration engineering; reconfigurable mechanism;
Conference_Titel :
Reconfigurable Mechanisms and Robots, 2009. ReMAR 2009. ASME/IFToMM International Conference on
Conference_Location :
London
Print_ISBN :
978-88-89007-37-2
Electronic_ISBN :
978-1-876346-58-4
