Title :
On-chip sub-cellular resolution whole-animal manipulation for high-throughput in vivo screening
Author :
Rohde, Christopher B. ; Zeng, Fei ; Gilleland, Cody ; Samara, Chrysanthi ; Yanik, Mehmet F.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Massachusetts Inst. of Technol., Cambridge, MA, USA
Abstract :
We present a suite of technologies that can be combined to perform complex high-throughput whole-animal genetic and drug screens. When used in various combinations, these devices facilitate a variety of high-throughput assays using whole animals.
Keywords :
biological techniques; cellular biophysics; zoology; drug screens; high-throughput assays; on-chip sub-cellular resolution; whole-animal genetic; whole-animal manipulation; Anesthetic drugs; Animals; Biomedical optical imaging; Genetics; In vivo; Large-scale systems; Libraries; Microfluidics; Stability; Ultrafast optics; (170.0170) Medical optics and biotechnology;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
