Title :
Sequential in vivo molecular imaging with a dual-axes confocal microscope
Author :
Ra, H. ; Gonzalez, E. ; Piyawattanametha, W. ; Mandella, M.J. ; Kaspar, R. ; Contag, C.H. ; Kino, G.S. ; Solgaard, O.
Author_Institution :
Edward L. Ginzton Lab., Stanford Univ., Stanford, CA, USA
Abstract :
We demonstrate sequential three-dimensional in vivo imaging in one mouse, monitoring siRNA silencing with a dual-axes confocal microscope. This opens up new possibilities in developing therapeutics for genetic disorders through better assessment of treatment efficiency.
Keywords :
biomedical optical imaging; genetics; molecular biophysics; optical microscopy; organic compounds; dual-axes confocal microscope; genetic disorders; mouse; sequential in vivo molecular imaging; siRNA silencing; therapeutics; Animals; Fluorescence; High-resolution imaging; In vivo; Medical treatment; Mice; Molecular imaging; Optical imaging; Optical microscopy; Skin; (170.1790) Confocal microscopy; (170.3880) Medical and biological imaging;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
