Title :
Atmospheric pressure femtosecond laser imaging mass spectrometry
Author :
Coello, Yves ; Gunaratne, Tissa C. ; Dantus, Marcos
Author_Institution :
Dept. of Chem., Michigan State Univ., East Lansing, MI, USA
Abstract :
We present a novel imaging mass spectrometry technique using femtosecond laser pulses to ionize the sample at atmospheric pressure and without the need of a laser-absorbing matrix. A 10 mum-resolution image of biological tissue is demonstrated.
Keywords :
biological tissues; high-speed optical techniques; image resolution; mass spectroscopy; optical pulse shaping; atmospheric pressure; biological tissue; femtosecond laser pulses; image resolution; imaging mass spectrometry; wavelength 10 mum; Adaptive optics; Chemical lasers; Ionization; Mass spectroscopy; Optical imaging; Optical pulse shaping; Particle beam optics; Pulse amplifiers; Skin; Ultrafast optics; (110.0110) Imaging systems; (170.0170) Medical optics and biotechnology; (320.0320) Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
