• DocumentCode
    500512
  • Title

    Real-time studies of muscle cell contractions with second harmonic generation microscopy

  • Author

    Prent, N. ; Cisek, R. ; Greenhalgh, C. ; Major, A. ; Stewart, B. ; Barzda, V.

  • Author_Institution
    Dept. of Phys., Univ. of Toronto, Mississauga, ON, Canada
  • fYear
    2009
  • fDate
    2-4 June 2009
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Real-time second harmonic generation microscopy of live myocytes was achieved with a femtosecond diode-pumped Yb:KGd(WO4)2 laser. Negligible absorption allows for prolonged imaging during muscle contractions with no significant phototoxic effects or signal degradation.
  • Keywords
    bio-optics; cellular biophysics; high-speed optical techniques; laser applications in medicine; muscle; optical harmonic generation; semiconductor lasers; femtosecond diode pumped laser; muscle cell contractions; myocytes; phototoxic effects; second harmonic generation microscopy; signal degradation; Absorption; Biomedical optical imaging; Diodes; Frequency conversion; Muscles; Nonlinear optics; Optical harmonic generation; Optical imaging; Optical microscopy; Ultrafast optics; (140.3615) Lasers, Ytterbium; (170.3880) Medical and Biological Imaging;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
  • Conference_Location
    Baltimore, MD
  • Print_ISBN
    978-1-55752-869-8
  • Electronic_ISBN
    978-1-55752-869-8
  • Type

    conf

  • Filename
    5225921