Title :
Visualizing cellular heterogeneity
Author :
Sott, Kristin ; Eriksson, Emma ; Goksör, Mattias
Author_Institution :
Dept. of Phys., Univ. of Gothenburg, Gothenburg, Sweden
fDate :
Oct. 30 2008-Nov. 2 2008
Abstract :
By combining optical manipulation, fluorescence microscopy and microfluidic devices we have studied the response from different signaling pathways in single Saccharomyces cerevisiae cells upon environmental perturbations. GFP-tagged proteins in the signaling pathway of interest visualized the heterogenic response within a population.
Keywords :
bioMEMS; biological techniques; cellular transport; fluorescence spectroscopy; microfluidics; optical microscopy; radiation pressure; GFP tagged proteins; Saccharomyces cerevisiae; cell signaling pathways; cellular heterogeneity visualisation; fluorescence microscopy; microfluidic devices; optical manipulation; Biomedical optical imaging; Charge carrier processes; Fluorescence; Holographic optical components; Holography; Microfluidics; Optical microscopy; Optical modulation; Proteins; Visualization;
Conference_Titel :
Optical Fiber Communication & Optoelectronic Exposition & Conference, 2008. AOE 2008. Asia
Conference_Location :
Shanghai
Print_ISBN :
978-1-55752-863-6
Electronic_ISBN :
978-1-55752-863-6