DocumentCode :
50579
Title :
Coupled Field Modeling of Ferrofluid Heating in Tumor Tissue
Author :
Mateev, Valentin ; Marinova, Iliana ; Saito, Yuya
Author_Institution :
Dept. of Electr. Apparatus, Tech. Univ. of Sofia, Sofia, Bulgaria
Volume :
49
Issue :
5
fYear :
2013
fDate :
May-13
Firstpage :
1793
Lastpage :
1796
Abstract :
This work examines the method of magnetic fluid hyperthermia for breast cancer therapy. We develop a coupled-field model of ferrofluid transport and heating in tumor tissue. The finite element method (FEM) underpins our forward 3D electromagnetic-fluid dynamics-thermal model. The model uses anatomically precise multilevel geometry of the human breast, with known electrical properties of the tissues, and known speeds of blood and liquor in the breast vessels. We demonstrate the capabilities of the developed model on a real cancer sample acquired by a surgical procedure. The electrical properties of cancer and normal tissues are directly measured for the given sample. The thermal field results are verified by infrared thermograph imaging.
Keywords :
bioelectric phenomena; biomedical optical imaging; blood vessels; cancer; finite element analysis; hyperthermia; infrared imaging; magnetic fluids; magnetic particles; physiological models; tumours; 3D electromagnetic-fluid dynamics-thermal model; FEM; anatomically precise human breast multilevel geometry; breast cancer therapy; breast vessel blood speed; breast vessel liquor speed; coupled field modeling; ferrofluid heating; ferrofluid transport; finite element method; infrared thermograph imaging; magnetic fluid hyperthermia; surgical procedure; tissues electrical properties; tumor tissue; Coupled field analysis; electromagnetic field modeling; magnetic liquids; multilevel modeling;
fLanguage :
English
Journal_Title :
Magnetics, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9464
Type :
jour
DOI :
10.1109/TMAG.2013.2242441
Filename :
6514549
Link To Document :
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