Title :
Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy
Author :
Zhuo, Shuangmu ; Chen, Jianxin ; Xie, Shusen ; Jiang, Xingshan ; Zheng, Liqin
Author_Institution :
Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou 350007, China
Abstract :
In dermis, collagen and elastin are important structural proteins of extracellular maxtrix. The matrix-disorder is associated with various physiologic processes, such as localized scleroderma, anetoderma, photoaging. In this work, we demonstrate the capability of nonlinear optical microscopy in imaging structural proteins in normal and pathological human dermis.
Keywords :
Biomedical optical imaging; Dermis; Humans; Nonlinear optics; Optical imaging; Optical microscopy; Optical sensors; Pathology; Proteins; Skin;
Conference_Titel :
Communications and Photonics Conference and Exhibition (ACP), 2009 Asia
Conference_Location :
Shanghai, China
Print_ISBN :
978-1-55752-877-3
Electronic_ISBN :
978-1-55752-877-3