Hybrid nano plasmonics for integrated biosensor

We reported recent efforts on further enhancement of SPR biosensors by the heterogeneous integration of organic electroluminescence light source and nano-grating structure for the feasibility study on the fast and high sensitivity detection of HBV isothermal amplification products, Mg2P2O7. We demonstrated the highly directional emissions through hybrid nano-grating structure corresponding to the resonant condition of SP modes and controllable band-gap by pitch modulation. The effective changes of refractive index resulted in color change at specific viewing angle. It can apply for the real time detection of HBV isothermal amplification in 30 minutes in the range from 5 to 5×10⁶ copies/25 ul.