Title :
Nonlinear endomicroscopy for two-photon autofluorescence imaging of biological tissues
Author :
Wu, Yicong ; Li, Ming-Jun ; Li, Xingde
Author_Institution :
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
Abstract :
A scanning fiber-optic endomicroscope with enhanced signal collection efficiency was developed for intrinsic two-photon fluorescence imaging of epithelial tissue. Ex vivo two-photon autofluorescence imaging were demonstrated for the first time from both epithelium and stroma of various biological tissues with such a flexible fiber-optic endomicroscope.
Keywords :
Biological tissues; Biomedical optical imaging; Fiber nonlinear optics; Fluorescence; Focusing; High-resolution imaging; Lenses; Nonlinear optics; Optical imaging; Optical sensors;
Conference_Titel :
Communications and Photonics Conference and Exhibition (ACP), 2009 Asia
Conference_Location :
Shanghai, China
Print_ISBN :
978-1-55752-877-3
Electronic_ISBN :
978-1-55752-877-3