• DocumentCode
    510876
  • Title

    Alterations of the ECM in ovarian carcinogenesis studied by second harmonic Generation imaging microscopy

  • Author

    Nadiarnykh, Oleg ; LaComb, Ronald B. ; Brewer, Molly A. ; Campagnola, Paul J.

  • Author_Institution
    University of Connecticut Health Center, Center for Cell Analysis and Modeling, Department of Cell Biology, Farmington, CT 06030, USA
  • fYear
    2009
  • fDate
    2-6 Nov. 2009
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We have used Second Harmonic Generation (SHG) imaging microscopy to quantify alterations in the fibrillar collagen assembly in ex vivo human malignant and normal ovarian tissues. We integrate 3D imaging measurements, bulk optical parameter measurements, and Monte Carlo simulations to isolate the structural factors that are different in these tissues.
  • Keywords
    Assembly; Cancer; Electrochemical machining; Frequency conversion; Humans; Integrated optics; Microscopy; Nonlinear optics; Optical harmonic generation; Optical imaging;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Communications and Photonics Conference and Exhibition (ACP), 2009 Asia
  • Conference_Location
    Shanghai, China
  • Print_ISBN
    978-1-55752-877-3
  • Electronic_ISBN
    978-1-55752-877-3
  • Type

    conf

  • Filename
    5377542
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=510876