• DocumentCode
    512345
  • Title

    Clinical diagnosis of oral submucous fibrosis with optical coherence tomography

  • Author

    Lee, Cheng-Kuang ; Tsai, Meng-Tsan ; Yang, C.C. ; Chiang, Chun-Pin

  • Author_Institution
    Institute of Photonics and Optoelectronics, National Taiwan University, 1, Roosevelt Road, Section 4, Taipei, 10617 Taiwan
  • Volume
    2009-Supplement
  • fYear
    2009
  • fDate
    2-6 Nov. 2009
  • Firstpage
    1
  • Lastpage
    8
  • Abstract
    A swept-source optical coherence tomography (SS-OCT) system with a specially designed probe is built for clinical scanning of oral submucous fibrosis (OSF) patients. By analysing 44 OSF cases of SS-OCT scanning results, two indicators, including epithelium (EP) thickness and standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer, are found useful for real-time OSF diagnosis. Statistics show that sensitivity and specificity of LP SD can reach 84.1 and 95.5 %, respectively. Also, both sensitivity and specificity of EP thickness can reach 100 %.
  • Keywords
    Biomedical optical imaging; Cancer; Clinical diagnosis; Fibroblasts; Humans; Mouth; Optical sensors; Photonics; Production; Tomography; Optical coherence tomography; medical and biological imaging; oral submucous fibrosis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Communications and Photonics Conference and Exhibition (ACP), 2009 Asia
  • Conference_Location
    Shanghai, China
  • Print_ISBN
    978-1-55752-877-3
  • Electronic_ISBN
    978-1-55752-877-3
  • Type

    conf

  • Filename
    5405627
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=512345