Title :
Waveguide biosensor with integrated photodetector array for tuberculosis serology
Author :
Yan, Rongjin ; Lynn, N. Scott ; Kingry, Luke C. ; Dandy, David S ; Slayden, Richard A ; Leara, Kevin L.
Author_Institution :
Dept. of Electr. & Comput. Eng., Colorado State Univ., Fort Collins, CO, USA
Abstract :
The first label-free LEAC biosensor immunoassay demonstration is reported. CMOS chips with integrated photoconductor arrays detected 150 kDa tuberculosis related antibodies and 18 kDa protein antigens. The limit of detection for thickness change was 120 pm.
Keywords :
CMOS integrated circuits; biosensors; integrated optoelectronics; optical waveguides; CMOS chips; biosensor immunoassay demonstration; integrated photoconductor arrays; integrated photodetector array; protein antigens; tuberculosis serology; waveguide biosensor; Biosensors; Detectors; Fluorescence; Immune system; Immunity testing; Intensity modulation; Optical waveguides; Photoconductivity; Photodetectors; Probes;
Conference_Titel :
Lasers and Electro-Optics (CLEO) and Quantum Electronics and Laser Science Conference (QELS), 2010 Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-890-2
Electronic_ISBN :
978-1-55752-890-2
