Title :
Label-free optofluidic biosensing in microplate, microfluidic, and spot-based affinity capture assays
Author :
Choi, Charles J. ; Belobraydich, Alysia R. ; Chan, Leo L. ; Mathias, Patrick C. ; Cunningham, Brian T.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA
Abstract :
Photonic crystal reflectance filters are co-fabricated/integrated with microfluidic channels on plastic substrates. Using the kinetic reaction rate constants measured, sensitivity limits and kinetic signal acquisition for label-free biosensing within various assay formats are studied.
Keywords :
Biosensors; Kinetic theory; Microfluidics; Optical filters; Optical sensors; Optoelectronic and photonic sensors; Photonic crystals; Resonance; Surface waves; Wavelength measurement;
Conference_Titel :
Lasers and Electro-Optics (CLEO) and Quantum Electronics and Laser Science Conference (QELS), 2010 Conference on
Conference_Location :
San Jose, CA, USA
Print_ISBN :
978-1-55752-890-2
Electronic_ISBN :
978-1-55752-890-2
