A Region-Based Approach for Investigating the Origin of Bioelectromagnetic Activities in MEG Source Space

In the present study, we develop a region-based approach, which integrates a novel bioelectromagnetic source inverse technique, together with the use of connectivity analysis method, i.e., directed transfer function (DTF), in investigating the origin of activities in MEG source space. The results confirm that the proposed approach is a promising noninvasive tool for the bioelectric field analysis and biomedical applications. In particular, since the regions are defined according to criteria of functional requirements for biomedical applications, the result obtained by the proposed method is easier to understand and interpret, and moreover, the result also facilitates inter-subject comparisons of the source connectivity analysis.