Title :
Multichannel bipotentiostat system for cellular monitoring platforms
Author :
Vergani, Marco ; Carminati, Marco ; Ferrari, Giorgio ; Adamovski, Miriam
Author_Institution :
Dipt. di Elettron. e Inf., Politec. di Milano, Milan, Italy
Abstract :
A versatile 4-channel bipotentiostat system for biochemical sensing is presented. A 1pA current resolution and 8 kHz bandwidth are suited for amperometric detection of neurotransmitters released by cells, monitored in a smart microfluidic culture chamber. Multiple electrochemical measurements can be carried out on arrays of microelectrodes. Key design issues are here discussed along with the results of extensive electrochemical experiments (cyclic voltammetry, chronoamperometry, redox recycling and potentiometry).
Keywords :
amperometric sensors; biochemistry; bioelectric potentials; biological techniques; cellular biophysics; microelectrodes; molecular biophysics; neurophysiology; oxidation; reduction (chemical); voltammetry (chemical analysis); 4-channel bipotentiostat system; amperometric detection; bandwidth 8 kHz; biochemical sensing; cellular monitoring; chronoamperometry; current 1 pA; cyclic voltammetry; microelectrode arrays; multichannel bipotentiostat system; neurotransmitters; potentiometry; redox recycling; smart microfluidic culture chamber; Bandwidth; Capacitance; Current measurement; Electric potential; Electrodes; Instruments; Noise; cell monitoring; electrochemical measurements; neurotransmitter detection;
Conference_Titel :
Ph.D. Research in Microelectronics and Electronics (PRIME), 2010 Conference on
Conference_Location :
Berlin
Print_ISBN :
978-1-4244-7905-4
