Title :
Mechanical properties in the ovariectomized rat model of osteoporosis after continuous and intermittent vibration
Author :
Sun, Dahui ; Zhao, Yi ; Tan, Lei ; Zhu, Dong ; Gao, Jiazi ; Zhang, Xizheng
Author_Institution :
Dept. of Traumatology of the First Hosp., Jilin Univ., Chang Chun, China
Abstract :
High frequency and low magnitude mechanical signal is endorsed as a new approach in preventing osteoporosis. The model of osteoporosis was established by forty-two wistar ovariectomized rats aged six months. Following a eight-week protocal composed of continuous and intermittent vibration, all the rats were executed by manual cervical dislocation. Biomechanical properties were determined by three point bending test of left ulnas and compression test of left tibial compact and cancellous bone. It was shown that the high frequency and low magnitude stimuli would prevent osteoporosis and the best effect was obtained in the IVGIO.
Keywords :
biomechanics; bone; orthopaedics; physiological models; biomechanical properties; biomechanics; cancellous bone; cervical dislocation; compression test; left tibial compact; osteoporosis; ovariectomized rat model; three point bending test; wistar ovariectomized rats; Bones; Loading; Osteoporosis; Rats; Testing; Vibrations; High frequency and low magnitude vibration; mechanical properties; osteoporosis; ovariectomized;
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference on
Conference_Location :
Yantai
Print_ISBN :
978-1-4244-6495-1
DOI :
10.1109/BMEI.2010.5639295
