Portable surface plasmon resonance instrument based on a monolithic scanner chip

Author

Cai, Haoyuan ; Li, Hui ; Zhang, Lulu ; Chen, Xing ; Cui, Dafu

Author_Institution

State Key Lab. of Transducer Technol., Chinese Acad. of Sci., Beijing, China

Volume

4

fYear

2010

fDate

16-18 Oct. 2010

Firstpage

1553

Lastpage

1555

Abstract

A portable Surface Plasmon Resonance (SPR) instrument based on a monolithic scanner chip-LM9833 was developed. With this compact design, the instrument can provide 16 bit grayscale resolution at 100 frames per second, support up to 16384 pixels linear CCD sensor, enable illumination control and USB interface. The instrument performance was tested and the refractive index sensitivity is about 6 × 10^-5 RIU (Refractive Index Unit). A direct immunoassay was carried out with this instrument and 15μg/ml Human Serum Albumin (HSA) could be detected.

Keywords

CCD image sensors; biosensors; monolithic integrated circuits; organic compounds; proteins; surface plasmon resonance; CCD sensor; Human Serum Albumin; LM9833 chip; USB interface; monolithic scanner chip; portable SPR instrument; portable surface plasmon resonance instrument; refractive index sensitivity; Charge coupled devices; Immune system; Instruments; Measurement by laser beam; Plasmons; Refractive index; Sensitivity; Biosensor; LM9833; Linear CCD; Surface Plasmon Resonance;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference on

Conference_Location

Yantai

Print_ISBN

978-1-4244-6495-1

Type

conf

DOI

10.1109/BMEI.2010.5639370

Filename

5639370