• DocumentCode
    534510
  • Title

    Electric-potential reconstructions of single particles using L2-gradient flows

  • Author

    Li, Ming ; Xu, Guoliang ; Sorzano, Carlos O S ; Melero, Roberto ; Bajaj, Chandrajit

  • Author_Institution
    State Key Lab. of Sci. & Eng. Comput., Acad. of Math. & Syst. Sci., Beijing, China
  • Volume
    1
  • fYear
    2010
  • fDate
    16-18 Oct. 2010
  • Firstpage
    213
  • Lastpage
    217
  • Abstract
    In this paper, we present a stable, reliable and robust method for reconstructing a three dimensional density function from a set of two dimensional electron microscopy images. By minimizing an energy functional consisting of a fidelity term and a regularization term, a L2-gradient flow is derived. The flow is integrated by a finite element method in the spatial direction and an explicit Euler scheme in temporal direction. The experimental results show that the proposed method is efficient and effective.
  • Keywords
    bioelectric potentials; electron microscopy; finite element analysis; image reconstruction; medical image processing; Euler scheme; L2-gradient flows; electric-potential reconstructions; energy functional; fidelity term; finite element method; regularization term; single particles; spatial direction; temporal direction; three dimensional density function; two dimensional electron microscopy images; Adenoviruses; Finite element methods; Image reconstruction; Microscopy; Spline; Three dimensional displays;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference on
  • Conference_Location
    Yantai
  • Print_ISBN
    978-1-4244-6495-1
  • Type

    conf

  • DOI
    10.1109/BMEI.2010.5639445
  • Filename
    5639445
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=534510