A theoretical model on thermal hysteresis activity of type III antifreeze protein

According to the properties of type III antifreeze protein (AFPIII) within the interfacial region of ice and water, the theoretical model of the large ligands binding on one-dimensional homogeneous lattice have been extended to two-dimensional lattice-like surface(ice surface). By using of this two-dimensional model, the fractions of the ice crystal surface covered by two type AFPIII variants that have different ice-binding face are calculated respectively. The thermal hysteresis activities of these proteins are obtained. The theoretical results are agreement with the reported experimental data.