• DocumentCode
    534927
  • Title

    Application of multi-centrality in human metabolism

  • Author

    De-Wu, Ding ; Xu-Dong, Liu

  • Author_Institution
    Dept. of Math. & Comput. Sci., Chizhou Coll., Chizhou, China
  • Volume
    1
  • fYear
    2010
  • fDate
    13-14 Sept. 2010
  • Firstpage
    198
  • Lastpage
    200
  • Abstract
    Lots of studies have focused on the structure and function of high-quality human metabolic networks. Recently, hub-based centrality is used to analysis of human metabolic network core. However, it is clear that this specific centrality measure is not sufficient alone. In the present paper, by comparing 10 different centrality measures with their application to human metabolic network core, be similar but smart, we give the top 10 center metabolites in the core, and discuss their biological and curatorial signification.
  • Keywords
    biochemistry; biocybernetics; molecular biophysics; network theory (graphs); network topology; centrality measure; high quality human metabolic network function; high quality human metabolic network structure; hub based centrality; human metabolic network core analysis; human metabolism; multicentrality; Computers; Diseases; Humans; Proteins; Publishing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computational Intelligence and Natural Computing Proceedings (CINC), 2010 Second International Conference on
  • Conference_Location
    Wuhan
  • Print_ISBN
    978-1-4244-7705-0
  • Type

    conf

  • DOI
    10.1109/CINC.2010.5643860
  • Filename
    5643860