The improved AMDF gene exon prediction

In order to improve the predictive accuracy and save the computation time, the improved average magnitude difference function (AMDF) is proposed in the paper. The AMDF was widely used to detect the gene exon as a time domain algorithm. In the paper the improved average magnitude difference function (AMDF) method-the sum of magnitude difference square function (SMDSF), which was proposed in the music signal processing, are firstly utilized in the gene detection. The predictive accuracy of the coding regions has increased 10% and 2% respectively for two different sequences and 5% as the statistical result for the GENESCAN database at a 10% false positive rate. SMDSF not only increases significantly in all kinds of performance index but also shorten the running time.