Fabrication of micro-platform for biological cell investigation

Author

Kusko, Mihaela S. ; Craciunoiu, Florea ; Gheorghe, Florentina ; Simion, Monica ; Bragaru, Adina ; Iordanescu, Andra ; Pascu, Razvan

Author_Institution

IMT Bucharest, Bucharest, Romania

Volume

1

fYear

2011

fDate

17-19 Oct. 2011

Firstpage

109

Lastpage

112

Abstract

In this paper we present the development / microfabrication of a device for the study of neuronal and cellular networks, useful to stimulate and record signals of both electrical and chemical nature. Being 3D type electrodes with tip dimension in nanometric range, the cells can survive even though they are penetrate by nanoelectrodes, and consequently the Si chip acts as a micro-platform to accommodate the neuronal cells and allows much finer temporal resolution of multisite electrical stimulation and recording without any damage to the investigated cells.

Keywords

bioMEMS; bioelectric phenomena; biomedical electrodes; cellular biophysics; lab-on-a-chip; microfabrication; nanobiotechnology; neurophysiology; silicon; 3D type electrodes; Si; biological cell investigation; cellular networks; chemical nature; chip; electrical nature; microfabrication; microplatform; multisite electrical stimulation; nanoelectrodes; neuronal cells; neuronal networks; Biological neural networks; Contacts; Electrodes; Fabrication; Nanobioscience; Silicon; Three dimensional displays; electrical signals; nanoelectrode; neuronal cells;

fLanguage

English

Publisher

ieee

Conference_Titel

Semiconductor Conference (CAS), 2011 International

Conference_Location

Sinaia

ISSN

1545-827X

Print_ISBN

978-1-61284-173-1

Type

conf

DOI

10.1109/SMICND.2011.6095728

Filename

6095728