Fabrication of nanostructured polymeric films and their geometric effects on cell growth

Author

Wang, Xi ; Wang, Yan-Yan ; Gu, Zhong-Ze ; Huang, Ning-Ping

Author_Institution

State Key Lab. of Bioelectronics, Southeast Univ., Nanjing, China

Volume

3

fYear

2011

fDate

15-17 Oct. 2011

Firstpage

1228

Lastpage

1231

Abstract

Nanoscaled inverse opal colloid crystal scaffolds with tunable structure based on various biomedical polymers have been fabricated via colloidal crystal templates. Bone marrow-derived mesenchyme stem cells (MSCs) were used to test the cellular compatibility of these nanostructured polymeric films. Cell morphology and viability were investigated by SEM and fluorescence staining, respectively. The results indicate that the MSCs can sense the nanoscale topographic features and grow well on the inverse opal scaffolds, which may imply potential applications in tissue engineering.

Keywords

biomedical materials; bone; cellular biophysics; colloidal crystals; fluorescence; nanobiotechnology; nanofabrication; nanostructured materials; polymer films; scanning electron microscopy; tissue engineering; SEM; biomedical polymers; bone marrow-derived mesenchyme stem cells; cell growth; cell morphology; cellular compatibility; colloidal crystal templates; fluorescence staining; geometric effects; nanoscale topographic features; nanoscaled inverse opal colloid crystal scaffolds; nanostructured polymeric films; tissue engineering; Colloidal crystals; Films; Nanobioscience; Plastics; Scanning electron microscopy; Substrates; Inverse opal scaffolds; Mesenchyme stem cells; Nanostructure; Nanotopography; Tissue engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics (BMEI), 2011 4th International Conference on

Conference_Location

Shanghai

Print_ISBN

978-1-4244-9351-7

Type

conf

DOI

10.1109/BMEI.2011.6098590

Filename

6098590