The influence of the ceramic phase on the structure of resorbable biocomposites based on collagen

Author

Antoniac, I. ; Vrânceanu, M.D. ; Antoniac, A. ; Albu, M.G.

Author_Institution

Univ. Politeh. of Bucharest, Bucharest, Romania

fYear

2011

fDate

24-26 Nov. 2011

Firstpage

1

Lastpage

4

Abstract

Collagen: hidroxyapatite and collagen: betatricalcium compositions were prepared by lyophylization and spongious composites for regeneration of bone defects were obtained. The spongious composites were characterized by Fourier transform infra-red (FT-IR) spectroscopy, scanning electron microscopy (SEM) and enzymatic degradation by collagenase. The results showed spongious composites with interconected pores of 20-150 μm with embedded particles of mineral phase. Their biodegradation is less for composite with 25:75 (Coll/HAp or Coll/ β-TCP) as results of FT-IR and collagenase degradation showed. Due to their properties, the obtained composites could be potential biomaterials for bone tissue engineering.

Keywords

Fourier transform spectra; bioceramics; biochemistry; biodegradable materials; bone; calcium compounds; composite materials; enzymes; infrared spectra; molecular biophysics; scanning electron microscopy; tissue engineering; Ca₁₀(PO₄)₆(OH)₂; FTIR; Fourier transform infrared spectroscopy; SEM; betatricalcium compositions; biodegradation; biomaterials; bone defect generation; bone tissue engineering; ceramic phase; collagen; collagenase; embedded particles; enzymatic degradation; hidroxyapatite; lyophylization; resorbable biocomposites; scanning electron microscopy; size 20 mum to 150 mum; spongious composites; Bones; Ceramics; Chemicals; Degradation; Minerals; Scanning electron microscopy; betatricalcium phosphate; collagen; composites; hydroxyapatite;

fLanguage

English

Publisher

ieee

Conference_Titel

E-Health and Bioengineering Conference (EHB), 2011

Conference_Location

Iasi

Print_ISBN

978-1-4577-0292-1

Type

conf

Filename

6150354