Title :
Fuzzy inference to decision support for SNP discovery
Author :
Arbex, Wagner ; Martins, Marta ; Silva, Marcos Vinícius ; Carvalho, Luís Alfredo
Author_Institution :
Centro Nac. de Pesquisa de Gado de Leite, Empresa Brasileira de Pesquisa Agropecuaria, Juiz de Fora, Brazil
Abstract :
A single difference between base pairs of different aligned sequences is the most common type of genetic variability and it are called Single Nucleotide Polymorphisms (SNPs). They are crucial for the study of species variability, since they can cause functional or phenotypic modifications which, in turn, may imply in evolutionary or biochemical consequences in the individuals of a given species. SNPs discovery is made through several mathematical and computational models. This paper presents a model which uses fuzzy logic as the basis for the development of an inference system to aid decision making, which is based on previous results obtained by different SNP discovery tools and which present possibly conflicting results.
Keywords :
DNA; biology computing; decision making; decision support systems; fuzzy logic; fuzzy reasoning; SNP discovery; biochemical consequences; decision making; decision support system; evolutionary consequences; functional modifications; fuzzy inference; fuzzy logic; genetic variability; phenotypic modifications; single nucleotide polymorphisms; species variability; Bioinformatics; Biological system modeling; Computational modeling; DNA; Genomics; Global Positioning System; Mathematical model; computational modeling; decision support; fuzzy inference; mathematical modeling; single nucleotide polymorphisms;
Conference_Titel :
Information Systems and Technologies (CISTI), 2012 7th Iberian Conference on
Conference_Location :
Madrid
Print_ISBN :
978-1-4673-2843-2