Title :
Change points in DNA coding sequences
Author :
Suvorova, Yulia ; Korotkov, Eugene
Author_Institution :
Bioinf. Lab., Centre of Bioeng., Moscow, Russia
Abstract :
We investigated genes that contain change points of triplet periodicity. The algorithm for detection of TP splicing of nucleotide sequences has been developed. Gene sequences from KEGG-48 databank were analyzed with a purpose of searching for genes with a TP change point. This change points were found in 311221 genes (~8% from the total number of genes in KEGG-48). We showed that the repetitive or low-complexity sequences are not cause of these events. We suppose that the TP change points may indicate fusion of genes or domains with different types of TP.
Keywords :
DNA; genetics; molecular biophysics; sequences; DNA coding sequence; KEGG-48 databank; TP change point; TP splicing detection; gene sequence; nucleotide sequence; triplet periodicity; Amino acids; Bioinformatics; DNA; Encoding; Genomics; Radio frequency; Random sequences; change points; fused genes; sequence analysis;
Conference_Titel :
Embedded Computing (MECO), 2012 Mediterranean Conference on
Conference_Location :
Bar
Print_ISBN :
978-1-4673-2366-6
