DocumentCode
573739
Title
A sequence-segmented method applied to the similarity analysis of proteins
Author
Kong, Fen ; Nan, Xu-ying ; He, Ping-an ; Dai, Qi ; Yao, Yu-hua
Author_Institution
Coll. of Sci., Zhejiang Sci-Tech Univ., Hangzhou, China
fYear
2012
fDate
18-20 Aug. 2012
Firstpage
321
Lastpage
326
Abstract
A 2-D graphical representation of protein sequences based on two classifications of amino acids is outlined. The method of dividing a long sequence into k segments (SSM) is introduced, so protein graph is divided into k segments, geometrical center of the points for all protein curve segment is given as descriptors of protein sequences. It is not only useful for comparative study of proteins, but also for encoding innate information about the structure of proteins. Finally, a simple example is taken to highlight the behavior of the new descriptor on protein sequences taken from the 12 baculoviruse proteins.
Keywords
bioinformatics; biological techniques; graph theory; molecular biophysics; molecular configurations; proteins; SSM; amino acid classification; baculovirus proteins; protein curve segment; protein graph; protein sequence 2D graphical representation; protein similarity analysis; sequence segmented method; Amino acids; Conferences; Protein sequence; Silicon; Systems biology; Vectors; Descriptors; Graphical representation; Sequence-Segmented Method; Similarity;
fLanguage
English
Publisher
ieee
Conference_Titel
Systems Biology (ISB), 2012 IEEE 6th International Conference on
Conference_Location
Xi´an
Print_ISBN
978-1-4673-4396-1
Electronic_ISBN
978-1-4673-4397-8
Type
conf
DOI
10.1109/ISB.2012.6314157
Filename
6314157
Link To Document