Fabrication and characterization of vertically aligned carbon nanofibers as a biosensor platform for hypoglycemia

Author

MacArthur, K.C. ; Tulip, Fahmida S. ; Mamun, K.A.A. ; McFarlane, Nicole ; Islam, Syed K.

Author_Institution

Dept. of Electr. Eng. & Comput. Sci., Univ. of Tennessee, Knoxville, TN, USA

fYear

2012

fDate

7-9 Aug. 2012

Firstpage

1

Lastpage

4

Abstract

This paper proposes a biosensor platform based on vertically aligned carbon nanofibers (VACNFs) for selective and sensitive detection of low levels of glucose to monitor the risks of hypoglycemia. Two enzymes, horseradish peroxidase and glucose oxidase, are co-immobilized on the nanofiber electrodes to make an electrochemical amperometric bienzymatic glucose biosensor. Experimental results indicate that the biosensor can detect glucose at the hypoglycemia levels (below 3.88 mM or 70 mg/dL).

Keywords

biochemistry; bioelectric potentials; biomedical electrodes; blood; carbon nanotubes; diseases; electrochemical analysis; electrochemical sensors; enzymes; molecular biophysics; nanofabrication; nanofibres; nanomedicine; sugar; C; biosensor platform; electrochemical amperometric bienzymatic glucose biosensor; enzymes; glucose detection; glucose oxidase; horseradish peroxidase; hypoglycemia; nanofabrication; nanofiber electrodes; vertically aligned carbon nanofibers; Biosensors; Carbon; Diabetes; Electrodes; Silicon; Sugar; VACNF; glucose biosensor; glucose oxidase; horseradish peroxidase; hypoglycemia; vertically aligned carbon nanofibers;

fLanguage

English

Publisher

ieee

Conference_Titel

Lester Eastman Conference on High Performance Devices (LEC), 2012

Conference_Location

Singapore

Print_ISBN

978-1-4673-2298-0

Electronic_ISBN

978-1-4673-2300-0

Type

conf

DOI

10.1109/lec.2012.6410986

Filename

6410986