Estimating infarct severity from the ECG using a realistic heart model

Author

van Dam, Peter M. ; Dijk, W. Arnold ; van der Putten, Niek Hjj ; Maan, Arie C. ; de Jongste, M.J.J.

Author_Institution

Radboud Univ. Med. Center, Nijmegen, Netherlands

fYear

2012

fDate

9-12 Sept. 2012

Firstpage

333

Lastpage

336

Abstract

The early phase of myocardial infarction is accompanied by changes in the ST segment of the ECG. This makes the ST segment the clinical marker for the detection of acute myocardial infarction. The determination of the infarct severity, location and size of the myocardial tissue at risk will support clinical decision making. In this study we used an inverse procedure to estimate the location and size of the infarcted heart region. The method estimates the local transmembrane amplitude based on the ECG amplitude near the J-point of the standard 12 leads signals using a patient specific volume conductor model. For the 5 available patient cases the positions as well as the size of the estimated infarct region were in accordance with results based on MRI.

Keywords

biological tissues; biomedical MRI; biomembranes; cellular biophysics; decision making; electrocardiography; medical signal processing; ECG; ECG amplitude; J-point; MRI; ST segment; acute myocardial infarction detection; clinical decision making; clinical marker; infarct severity; infarcted heart region; inverse procedure; local transmembrane amplitude; myocardial tissue; patient specific volume conductor model; realistic heart model; Conductors; Electrocardiography; Heart; Magnetic resonance imaging; Myocardium; Solid modeling; Standards;

fLanguage

English

Publisher

ieee

Conference_Titel

Computing in Cardiology (CinC), 2012

Conference_Location

Krakow

ISSN

2325-8861

Print_ISBN

978-1-4673-2076-4

Type

conf

Filename

6420398