Title :
Metal-enhanced fluorescence in liposomes for photothermal studies
Author :
Lee, E.M.Y. ; Yong, Z.Y.D. ; Xia Yu ; Chi Chiu Chan
Author_Institution :
Sch. of Chem. & Biomed. Eng., Nanyang Technol. Univ., Singapore, Singapore
Abstract :
Fluorescence has been used in many different fields such as imaging and sensing. Fluorescence self-quenching is a unique property that occurs at high concentrations, resulting in reduced emission intensities. This study aims to demonstrate the emission enhancement of fluorescein encapsulated in liposomes. The emission was observed to be enhanced when gold nanoparticles were added to liposome-encapsulated fluorescein, while quenching effect was still observed for released fluorescein. These effects can then be accounted for in future plasmonic photothermal effect studies.
Keywords :
biomembranes; biothermics; dyes; fluorescence; gold; lipid bilayers; molecular biophysics; nanobiotechnology; nanoparticles; photothermal effects; plasmonics; radiation quenching; Au; Iiposome-encapsulated fluorescein; emission enhancement; emission intensity; fluorescence self-quenching; gold nanoparticles; metal-enhanced fluorescence; plasmonic photothermal effect; quenching effect; Fluorescence; Gold; Heating; Medical services; Nanoparticles; Nitrogen; fluorescein; gold nanoparticle; liposome; metal-enhanced;
Conference_Titel :
Photonics Global Conference (PGC), 2012
Conference_Location :
Singapore
Print_ISBN :
978-1-4673-2513-4
DOI :
10.1109/PGC.2012.6458005