Characterization of biological substances using a substrate integrated microwave near-field sensor

Author

Haase, Nora ; Jacob, A.F.

Author_Institution

Inst. fur Hochfrequenztech., Techn. Univ. Hamburg-Harburg, Hamburg, Germany

fYear

2012

fDate

Oct. 29 2012-Nov. 1 2012

Firstpage

432

Lastpage

435

Abstract

Measurements performed with a 3.1 GHz substrate integrated near-field sensor on aqueous solutions are reported. The samples include Chinese hamster ovary (CHO) cells in a culture medium as a representative and easily reproducible biological environment. The permittivity contrast between the cells and the surrounding medium is estimated based on perturbation theory. The resolution and sensitivity required for a device capable of single cell measurements at microwave frequencies are discussed based on these results.

Keywords

bioelectric phenomena; biosensors; cellular biophysics; microwave detectors; microwave integrated circuits; permittivity; perturbation theory; sensitivity; Chinese hamster ovary cells; aqueous solutions; biological environment; biological substances characterization; culture medium; frequency 3.1 GHz; microwave frequencies; permittivity contrast; perturbation theory; sensitivity; single cell measurements; substrate integrated microwave near-field sensor; Frequency measurement; Microwave imaging; Microwave measurements; Permittivity; Permittivity measurement; Q factor; Resonant frequency;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave Conference (EuMC), 2012 42nd European

Conference_Location

Amsterdam

Print_ISBN

978-1-4673-2215-7

Electronic_ISBN

978-2-87487-026-2

Type

conf

Filename

6459197