• DocumentCode
    60417
  • Title

    Prediction of Tubulin Resonant Frequencies Using the Resonant Recognition Model (RRM)

  • Author

    Cosic, Irena ; Lazar, Katarina ; Cosic, Drasko

  • Author_Institution
    RMIT Univ., Melbourne, VIC, Australia
  • Volume
    14
  • Issue
    4
  • fYear
    2015
  • fDate
    Jun-15
  • Firstpage
    491
  • Lastpage
    496
  • Abstract
    Tubulin proteins were analyzed using the Resonant Recognition Model to predict possible electromagnetic resonances in tubulin and microtubules. We propose that these electromagnetic resonances are caused by charge transfer through the protein molecule. The frequencies of these electromagnetic resonances depend on charge velocity. Using different velocities of charge transfer, we predicted resonant frequencies in different frequency ranges from KHz to THz. These resonant frequencies could be relevant for taxol binding as well as a possible role of microtubules as a macromolecular computer.
  • Keywords
    charge exchange; molecular biophysics; physiological models; proteins; charge transfer velocities; electromagnetic resonance prediction; macromolecular computer; microtubules; protein molecule; resonant recognition model; taxol binding; tubulin resonant frequency; Amino acids; Charge transfer; Phonons; Proteins; Resonant frequency; Molecular modeling; protein resonances; resonant recognition model; signal processing; tubulin;
  • fLanguage
    English
  • Journal_Title
    NanoBioscience, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    1536-1241
  • Type

    jour

  • DOI
    10.1109/TNB.2014.2365851
  • Filename
    6967834