Title :
Cell manipulation systems using dielectrophoretic process for diagnostic sensors
Author :
Hyunsang Joo ; Yunho Kim ; Misun Cha ; Junghoon Lee
Author_Institution :
Sch. of Mech. & Aerosp. Eng., Seoul Nat. Univ., Seoul, South Korea
Abstract :
This paper demonstrated the effectiveness of Dielectrophoresis (DEP) on microfluidic devices as part of diagnostic sensors. It was possible to focus bacterial cells into the intended area based on droplet evaporation on hydrophobic guide structure and DEP force with micro-patterned electrodes. Similarly, we dealt with separation of blood cells from whole blood so that plasma can be applied in many biomedical fields. The micro fluidic channels were attached on both sides of the device which includes electrodes for DEP and pore-array membrane. Micro-sized beads were experimented prior to realizing those two functions of DEP on biological cells.
Keywords :
bioMEMS; blood; cellular biophysics; drops; electrochemical electrodes; electrochemical sensors; electrophoresis; evaporation; hydrophobicity; microfabrication; microfluidics; microorganisms; DEP force; bacterial cells; biomedical fields; blood cell separation; blood plasma; cell manipulation systems; diagnostic sensors; dielectrophoretic process; droplet evaporation; hydrophobic guide structure; microfluidic channels; micropatterned electrodes; microsized beads; pore-array membrane;
Conference_Titel :
Nanotechnology Materials and Devices Conference (NMDC), 2012 IEEE
Conference_Location :
Waikiki Beach, HI
Print_ISBN :
978-1-4673-2871-5
DOI :
10.1109/NMDC.2012.6527606