Subcellular near-field biomolecule sampling using a biosensor

Author

Qi Xia ; Hughes, Ashley ; Raghu, Deepa ; Reeves, Mark

Author_Institution

Dept. of Phys., George Washington Univ., Washington, DC, USA

fYear

2013

fDate

14-14 May 2013

Firstpage

31

Lastpage

34

Abstract

As the initial experiments towards integrating the near-field ablation and a fiber-optic biosensor, we report the near-field ablation on Arabidopsis thaliana leaf samples with a 2μm ablation spot. We also report time-dependent spectral plots of detecting biomolecules in the ground Arabidopsis leaf solution. The sensitivity of detecting biomolecules with amino functional groups was improved by using a biosensor coated with a specific type of cross linkers.

Keywords

biosensors; botany; cellular biophysics; fibre optic sensors; molecular biophysics; Arabidopsis thaliana leaf samples; amino functional groups; biomolecules; cross linkers; fiber-optic biosensor; near-field ablation; size 2 mum; subcellular near-field biomolecule sampling; time-dependent spectral plots; Biosensors; Laser ablation; Optical fiber couplers; Optical fiber sensors; Probes; Proteins; Arabidopsis thaliana; Near-field ablation; fiber-optic biosensor; subcellular level;

fLanguage

English

Publisher

ieee

Conference_Titel

Microsystems for Measurement and Instrumentation (MAMNA), 2013

Conference_Location

Gaithersburg, MD

Print_ISBN

978-1-4799-0221-7

Type

conf

DOI

10.1109/MAMNA.2013.6557233

Filename

6557233