Evolutionary medical image registration using automatic parameter tuning

Image registration is a fundamental step in combining information from multiple images in medical imaging, computer vision and image processing. In this paper, we configure a recent evolutionary algorithm for medical image registration, r-GA, with an offline automatic parameter tuning technique. In addition, we demonstrate the use of automatic tuning to compare different registration algorithms, since it allows to consider results that are not affected by the ability and efforts invested by the designers in configuring the different algorithms, a crucial task that strongly impacts their performance. Our experimental study is carried out on a large dataset of brain MRI, on which we compare the performance of r-GA with four classic IR techniques. Our results show that all algorithms benefit from the automatic tuning process and indicate that r-GA performs significantly better than the competitors.