Title :
A Dual Mode Neural Signal Recording System for synchronous neuroeletrical and neurochemical detection
Author :
Shengwei Xu ; Nansen Lin ; Dalei Wang ; Wenjing Yu ; Wentao Shi ; Tingjun Jiang ; XinXia Cai
Author_Institution :
State Key Lab. of Transducer Technol., Inst. of Electron., Beijing, China
Abstract :
This paper presents a 64-channel Dual Mode Neural Signal Recording System (DMNSRS) for detection of neuroeletrical and neurochemical signals. The DMNSRS comprises neurochemical recording module with current resolution of 1 pA and neuroelectricity recording module with voltage resolution of 0.3 μV. The two modules can work synchronously without mutual interference. In a global cerebral ischemia experiment, using Multi-Electrode Arrays (MEA) as neurobiological electrode and a single-walled carbon nanotube (SWNT)-modified glassy carbon electrode as neurochemical working electrode, the neuroelectrical and neurochemical signals are synchronously recorded by the DMNSRS in the Sprague-Dawley (SD) rat cortex.
Keywords :
bioelectric phenomena; biomedical electrodes; carbon nanotubes; medical signal detection; nanomedicine; neurophysiology; 64-channel dual mode neural signal recording system; C; DMNSRS; SWNT; Sprague-Dawley rat cortex; current resolution; global cerebral ischemia experiment; multielectrode arrays; neurobiological electrode; neurochemical recording module; neurochemical signal detection; neurochemical working electrode; neuroelectricity recording module; neuroeletrical signal detection; single-walled carbon nanotube-modified glassy carbon electrode; synchronous neuroeletrical detection; voltage resolution; Band-pass filters; Carbon nanotubes; Data acquisition; Differential amplifiers; Electrodes; Gain; Oxidation; ascorbic acid; cerebral ischemia; dual mode recording; neurochemical; neuroeletrical;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems (NEMS), 2013 8th IEEE International Conference on
Conference_Location :
Suzhou
Electronic_ISBN :
978-1-4673-6351-8
DOI :
10.1109/NEMS.2013.6559772
