Title :
Near-random usage of synonymous codon in Nlrp1
Author :
Sim-Hui Tee ; Sin-Liang Lim ; Sin-Ting Lim
Author_Institution :
Multimedia Univ., Cyberjaya, Malaysia
Abstract :
Synonymous codon usage is a ubiquitous phenomenon in the genes of organisms. It is a phenomenon that is closely associated with gene expression level, understanding of which may have practical applicability in biomedicine sector. In this study, the synonymous codon usage in Nlrp1 gene was investigated. Because Nlrp1 gene encodes for NLRP1 inflammasome, which is an important cytosolic pathogen sensor in the immune system, our results may shed light in the immunopathology and therapeutic strategies.
Keywords :
diseases; genetics; medical computing; NLRP1 inflammasome; Nlrp1 gene encoding; biomedicine sector; cytosolic pathogen sensor; gene expression level; immune system; immunopathology; organisms; synonymous codon near-random usage; therapeutic strategy; Amino acids; Bioinformatics; Gene expression; Genomics; Immune system; Organisms; Proteins; Nlrp1; bioinformatics; gene; scientific computing; synonymous codon;
Conference_Titel :
Business Engineering and Industrial Applications Colloquium (BEIAC), 2013 IEEE
Conference_Location :
Langkawi
Print_ISBN :
978-1-4673-5967-2
DOI :
10.1109/BEIAC.2013.6560261
