Title :
Preparation of Nanotubular PDMS/PVC Molds for Reduced Catheter Inflammation and Infection
Author :
Luting Liu ; Webster, Thomas J.
Author_Institution :
Dept. of Chem. Eng., Northeastern Univ., Boston, MA, USA
Abstract :
Inflammation and infection of catheters (and polymeric medical devices in general) is a significant problem. Previous studies have demonstrated that metals with nanotubular surface features can decrease both inflammatory and bacteria functions. With this in mind, this study aimed to create polydimethylsiloxane (PDMS)/polyvinyl chloride (PVC) molds out of anodized titanium (Ti) in order to transfer this novel antibacterial surface roughness to polymers. In addition, such polymers were further tested for inflammatory and bacteria responses.
Keywords :
anodisation; antibacterial activity; catheters; diseases; microorganisms; nanofabrication; nanomedicine; nanostructured materials; polymers; surface roughness; titanium; Ti; anodized titanium; antibacterial surface roughness; bacteria functions; bacteria responses; catheter infection; catheter inflammation; inflammatory functions; nanotubular PDMS-PVC mold preparation; nanotubular surface features; polydimethylsiloxane-polyvinyl chloride molds; polymers; Catheters; Electron tubes; Microorganisms; Nanotubes; Platinum; Surface treatment; Titanium; PDMS; PVC; anodized titanium;
Conference_Titel :
Bioengineering Conference (NEBEC), 2013 39th Annual Northeast
Conference_Location :
Syracuse, NY
Print_ISBN :
978-1-4673-4928-4
DOI :
10.1109/NEBEC.2013.128
