Preparation of Nanotubular PDMS/PVC Molds for Reduced Catheter Inflammation and Infection

Author

Luting Liu ; Webster, Thomas J.

Author_Institution

Dept. of Chem. Eng., Northeastern Univ., Boston, MA, USA

fYear

2013

fDate

5-7 April 2013

Firstpage

74

Lastpage

75

Abstract

Inflammation and infection of catheters (and polymeric medical devices in general) is a significant problem. Previous studies have demonstrated that metals with nanotubular surface features can decrease both inflammatory and bacteria functions. With this in mind, this study aimed to create polydimethylsiloxane (PDMS)/polyvinyl chloride (PVC) molds out of anodized titanium (Ti) in order to transfer this novel antibacterial surface roughness to polymers. In addition, such polymers were further tested for inflammatory and bacteria responses.

Keywords

anodisation; antibacterial activity; catheters; diseases; microorganisms; nanofabrication; nanomedicine; nanostructured materials; polymers; surface roughness; titanium; Ti; anodized titanium; antibacterial surface roughness; bacteria functions; bacteria responses; catheter infection; catheter inflammation; inflammatory functions; nanotubular PDMS-PVC mold preparation; nanotubular surface features; polydimethylsiloxane-polyvinyl chloride molds; polymers; Catheters; Electron tubes; Microorganisms; Nanotubes; Platinum; Surface treatment; Titanium; PDMS; PVC; anodized titanium;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference (NEBEC), 2013 39th Annual Northeast

Conference_Location

Syracuse, NY

ISSN

2160-7001

Print_ISBN

978-1-4673-4928-4

Type

conf

DOI

10.1109/NEBEC.2013.128

Filename

6574364