DocumentCode
62818
Title
An Innovative Design for In-Vitro Fertilization Oocyte Retrieval Systems
Author
Kok Kiong Tan ; Sunan Huang ; Minh Hoang-Tuan Nguyen ; Wenyu Liang ; Soon-Chye Ng
Author_Institution
Dept. of Electr. & Comput. Eng., Nat. Univ. of Singapore, Singapore, Singapore
Volume
9
Issue
4
fYear
2013
fDate
Nov. 2013
Firstpage
1892
Lastpage
1899
Abstract
In-vitro fertilization (IVF) and related technologies are arguably the most challenging of all cell culture applications. This paper introduces a new design of an integrated oocyte retrieval solution before the oocytes are further put into laboratory processing during IVF treatment. It facilitates the surgery operation and addresses the temperature inaccuracy of follicular fluid during the transfer to the patient´s body. The mechanical design is implemented into a medical-standard conforming platform. An accurate temperature estimation and optimization scheme is also proposed. Comparison before and after the introduction of the new prototype under various operating conditions reveals a significant improvement in performance. This yields a potential application for the medical/healthcare industry.
Keywords
cellular biophysics; control system synthesis; gynaecology; medical control systems; observers; predictive control; surgery; temperature control; IVF treatment; MPC; cell culture application; follicular fluid; healthcare industry; in-vitro fertilization oocyte retrieval systems; innovative design; laboratory processing; mechanical design; medical industry; medical-standard conforming platform; model predictive control; observer; patient body; programmable logic control; surgery operation; temperature estimation; temperature inaccuracy; temperature optimization; In vitro fertilization; Medical services; Observers; Predictive control; Temperature measurement; Temperature sensors; IVF; medical device; model predictive control; sliding mode observer;
fLanguage
English
Journal_Title
Industrial Informatics, IEEE Transactions on
Publisher
ieee
ISSN
1551-3203
Type
jour
DOI
10.1109/TII.2012.2226467
Filename
6340340
Link To Document