DocumentCode
636222
Title
How do chondrocytes aggregate on fibroin substrate
Author
Otaka, Akihiro ; Takahashi, Koichi ; Isshiki, Kenji ; Kambe, Yusuke ; Kojima, Keisuke ; Tamada, Yasushi ; Tomita, N.
Author_Institution
Grad. Sch. of Eng., Dept. of Mech. Eng. & Sci., Kyoto Univ., Kyoto, Japan
fYear
2013
fDate
3-7 July 2013
Firstpage
405
Lastpage
408
Abstract
The effects of substrate material on the spatio-temporal behavior of cells is an important issue. Although cell aggregation has been observed on various fibroin substrates, the mechanisms of this aggregation have yet to be fully clarified. In this study, cell aggregation behavior on fibroin substrates were evaluated, focusing on the distance between each cell and the direction of individual cell migration. Our results showed that on fibroin substrates cells did not attract each other. However cells stayed close to adjacent cells over 24 hours of cultivation.
Keywords
aggregation; cell motility; molecular biophysics; proteins; spatiotemporal phenomena; cell aggregation behavior; cell spatiotemporal behavior; chondrocyte aggregation; fibroin substrate; individual cell migration direction; substrate material; Adhesives; Cells (biology); Educational institutions; Indexes; Kernel; Substrates;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location
Osaka
ISSN
1557-170X
Type
conf
DOI
10.1109/EMBC.2013.6609522
Filename
6609522
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