Title :
Noninvasive cellular quantity measurement in Bone Marrow Stromal Cells/ Beta-tricalcium phosphate
Author :
Yagi, Naomi ; Ishikawa, Takaaki ; Kuramoto, Koji ; Kobashi, Shoji ; Hata, Yuki
Author_Institution :
Grad. Sch. of Eng., Univ. of Hyogo, Himeji, Japan
Abstract :
This paper describes noninvasive cellular quantity measurement in Bone Marrow Stromal Cells/ β-tricalcium phosphate. We attempt to identify cellular quantity with an ultrasonic system. The ultrasonic waves are reflected at boundaries where there is a difference in acoustic impedances of the materials on each side of the boundary. Therefore, we focus on the reflected signal. From the obtained ultrasonic data, we extract two features; amplitude and frequency. Amplitude is obtained from the raw ultrasonic wave, and frequency is calculated from frequency spectrum obtained by applying cross-spectrum method. Therefore, we suggest the superiority of frequency to analyze Bone Marrow Stromal Cells. This study shows the ability of intervention to produce the desired beneficial effect.
Keywords :
bioceramics; biomedical ultrasonics; bone; cellular biophysics; tissue engineering; acoustic impedance; beta tricalcium phosphate; bone marrow stromal cells; cellular quantity identification; cross spectrum method; noninvasive cellular quantity measurement; reflected ultrasonic signal; ultrasonic system; ultrasonic wave reflection; Acoustics; Attenuation; Bones; Educational institutions; Materials; Ultrasonic imaging; Ultrasonic variables measurement;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6609934