Near-infrared spectroscopy system for determining brain hemoglobin level

Author

Pei-Jung Wu ; Ming-Hsien Chang ; Cheng-Yang Huang ; Yu-Cheng Wang ; Jinn-Rung Kuo ; Yan-Jun Huang ; Bor-Shyh Lin

Author_Institution

Inst. of Imaging & Biomed. Photonics, Nat. Chiao Tung Univ., Hsinchu, Taiwan

fYear

2013

fDate

3-7 July 2013

Firstpage

2412

Lastpage

2414

Abstract

Traumatic brain injury (TBI) usually results from brain shaking or impact. It can affect the normal function of the brain and even cause people become disabled and death. However, there is lack of studies for the physiological changes of humans or animals under brain injury. In order to obtain the information of physiological state change, we designed and enforced a non-invasive, wireless multi-channel near-infrared spectroscopy (NIRS) for monitoring the concentration change of oxy-hemoglobin (HbO₂), deoxy-hemoglobin (HbR) and total-hemoglobin (HbT) continuously during and after TBI. The experimental results indicated that the concentration change of HbO₂ and HbT is significantly related to the impact strength and infarction volume. Thus, this system is easily used and stable for TBI study.

Keywords

biochemistry; biomedical optical imaging; brain; infrared spectra; injuries; molecular biophysics; neurophysiology; patient monitoring; proteins; brain function; brain impact strength; brain shaking; deoxyhemoglobin concentration change monitoring; infarction volume; physiological state change; total-hemoglobin concentration change monitoring; traumatic brain injury; wireless multichannel near-infrared spectroscopy system; Biomedical monitoring; Blood flow; Brain injuries; Monitoring; Probes; Spectroscopy; Wireless communication;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE

Conference_Location

Osaka

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2013.6610025

Filename

6610025