Determination of the competitive ion exchange isotherms of taurine and glycine on D290 resin by inverse method

With the elution curves of glycine and taurine, the ion exchange isotherm parameters of glycine and taurine on D290 anion exchange resin are determined by the inverse method. In this work, with the multi-component competitive ion exchange isotherm and the equilibrium dispersion chromatographic model, the elution curves of glycine and taurine on D290 anionic fixed bed are fitted. The parameters of competitive isotherm are determined, K_tau is 2.55, K_gly is 1.65. The result s showed good agreement between the elute curves fitted by the model and the separation data which confirmed the validity of the model selected.