Evaluation of intracellular water dynamics in the picosecond timescales investigated by terahertz spectroscopy

Author

Shiraga, Keiichiro ; Ogawa, Y. ; Suzuki, Takumi ; Kondo, N. ; Irisawa, A. ; Imamura, Motoki

Author_Institution

Kyoto Univ., Kyoto, Japan

fYear

2013

fDate

1-6 Sept. 2013

Firstpage

1

Lastpage

2

Abstract

The complex dielectric constant of human cultured cell, HeLa, is determined in the terahertz region. Since they are sensitive to picosecond motions, intracellular water dynamics mediated by hydrogen bonds are discussed. As a result, it is suggested that about 25 % of water molecules are slightly perturbed and hydrogen bonds are more “unstructured” in the cellular milieu, indicating 6 % of total intracellular water molecules are isolated from hydrogen bond network of water.

Keywords

bioelectric phenomena; cellular biophysics; hydrogen bonds; molecular biophysics; permittivity; terahertz wave spectra; water; HeLa cell; cellular milieu; complex dielectric constant; human cultured cell; hydrogen bond network; intracellular water dynamics; intracellular water molecules; picosecond motions; terahertz region; terahertz spectroscopy; Dielectric constant; Dynamics; Electric fields; Hydrogen; Nanobioscience; Nuclear magnetic resonance; Spectroscopy;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2013 38th International Conference on

Conference_Location

Mainz

Type

conf

DOI

10.1109/IRMMW-THz.2013.6665883

Filename

6665883